Nesto Richard W
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA.
Rev Cardiovasc Med. 2006;7 Suppl 2:S18-24.
A substantial number of patients being evaluated or treated for cardiovascular disease are found to have glucometabolic disorders. Identification of such patients is important because treatment for coronary artery disease and stroke needs to be individualized. Hyperglycemia on admission or during hospitalization regardless of whether diabetes mellitus is known to exist in these patients is associated with increased morbidity and mortality. Despite the fact that this has been known for some time, various strategies to reduce hyperglycemia have had mixed results in cardiac outcomes. Another important factor is that a new diagnosis of diabetes mellitus in these patients should result in the patient's triage to appropriate healthcare professionals to optimize glycemic control. The prevalence of hyperglycemia in patients admitted with acute cardiovascular disease and the effect of hyperglycemia on outcome are reviewed.
大量正在接受心血管疾病评估或治疗的患者被发现存在糖代谢紊乱。识别这些患者很重要,因为冠状动脉疾病和中风的治疗需要个体化。无论这些患者是否已知患有糖尿病,入院时或住院期间的高血糖都与发病率和死亡率增加有关。尽管这一情况已为人所知有一段时间了,但各种降低高血糖的策略在心脏结局方面的结果参差不齐。另一个重要因素是,这些患者中新诊断出糖尿病应促使患者被分诊给合适的医疗专业人员,以优化血糖控制。本文综述了急性心血管疾病患者中高血糖的患病率以及高血糖对结局的影响。