Thoumazet François, Donnio Angélique, Ayeboua Lucas, Brebion Alain, Diedhou Abdoulaye, Merle Harold
Service d'Opthalmologie, Centre Hospitalier Universitaire de Fort de France, France.
Can J Ophthalmol. 2006 Dec;41(6):733-6. doi: 10.3129/i06-067.
We report 2 cases of orbital plasmacytoma in patients with known multiple myeloma. Orbital spread with secondary maxillary sinus involvement is reported in the first case. Case 2 is the first report of immunoglobulin A kappa light chain multiple myeloma involving orbital recti muscles. Computed axial tomography and magnetic resonance imaging aided the diagnosis, confirmed with histopathologic studies.
Extraskeletal spread is rare and orbital involvement is exceedingly uncommon. From a review of the literature since 1972, we conclude that the immunoglobulin G type of multiple myeloma, whether lambda or kappa light chain, may be a risk factor for orbital involvement.