Ibrik O, Samon R, Roca R, Viladoms J, Mora J
Sección de Nefrología, Hospital de Mollet, Sant LLorenç 39-41, 08100 Mollet del Vallès, Barcelona.
Nefrologia. 2006;26(6):719-25.
Review a large experience in the placement of tunnelled catheters to assess the outcomes with twin catheter system as hemodialysis access.
We retrospectively reviewed clinical and hemodialysis data regarding of ESRD patients who were referred from 2 dialysis facilities for placement of tunnelled catheters hemodialysis access between 1996 March and 2005 July. For catheter insertion a real-time sonography technique was used (Site Rite II Dymax corporation) in performing vascular access procedure. The twin catheter system available during the study period consisted of 2 x 10-F12. Patients suspected to present bacteraemia related to catheter were followed with established protocols. Catheter suspected malfunction or thrombosis was treated with low dose Urokinase. To evaluated dialysis dose and adequacy, blood flow rates were recorded and Kt/v calculated by Daugirdas 2nd generation formula.
Overall study period of 112 months, 210 catheters were inserted in 148 patients(93 males and 55 females, mean age 68,6 +/- 4,95 years). 101 catheters were inserted in internal jugular vein, 84 in femoral and 25 in subclavian. The successful insertion rate with only single needle pass was 87.8%, immediate procedural complications rate was 4.7%. The catheters were in place a total of 18,324 days during the study period (mean 87.2 days; range 4-1,280 days). The mean flow blood rate was 252,4 DS +/- 42.4 mL/min, Mean Kt/v was 1,21 DS +/- 0,07. Seventy-seven catheters malfunctioned during study period, in 55 cases urokinase was effective in recovering blood flow rate over 250 mL/min and 25 necessitated removal for ineffective urokinase. Infection incidence was 11.9% with bacteraemia related catheter rate of 2.8 episodes per 1,000 catheter-days, Gram positive bacteria was found in (84%), Gram negative in (12%) and others(4%).
Placement of tunnelled twin catheters system using real-time sonography technique can be performed with excellent technical success, safety and acceptable catheter performance and outcomes for effective hemodialysis.
回顾大量带隧道导管置入经验,以评估双导管系统作为血液透析通路的效果。
我们回顾性分析了1996年3月至2005年7月期间从2个透析机构转诊来行带隧道导管血液透析通路置入的终末期肾病(ESRD)患者的临床和血液透析数据。导管插入采用实时超声技术(Site Rite II,Dymax公司)进行血管通路操作。研究期间可用的双导管系统由2根10-F12导管组成。对怀疑与导管相关的菌血症患者按照既定方案进行随访。怀疑导管功能障碍或血栓形成时,用低剂量尿激酶治疗。为评估透析剂量和充分性,记录血流量并根据第二代Daugirdas公式计算Kt/v。
整个研究期112个月,148例患者(93例男性,55例女性,平均年龄68.6±4.95岁)共置入210根导管。101根导管插入颈内静脉,84根插入股静脉,25根插入锁骨下静脉。单针穿刺成功置入率为87.8%,即时操作并发症发生率为4.7%。研究期间导管共在位18324天(平均87.2天;范围4 - 1280天)。平均血流量为252.4±42.4 mL/分钟,平均Kt/v为1.21±0.07。研究期间7根导管出现功能障碍,55例中尿激酶有效恢复血流量至250 mL/分钟以上,25例因尿激酶无效而需拔除导管。感染发生率为11.9%,与导管相关的菌血症发生率为每1000导管日2.8次发作,革兰阳性菌占(84%),革兰阴性菌占(12%),其他占(4%)。
采用实时超声技术置入带隧道双导管系统技术成功率高、安全,导管性能和效果可接受,能有效进行血液透析。