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腹腔镜部分胃底折叠术对吞咽困难、食管及食管下括约肌动力的影响

The effect of laparoscopic partial fundoplication on dysphagia, esophageal and lower esophageal sphincter motility.

作者信息

Lindeboom M Y A, Ringers J, Straathof J-W A, van Rijn P J J, Neijenhuis P, Masclee A A M

机构信息

Department of Gastroenterology-Hepatology, Leiden University Medical Center, Leiden, the Netherlands.

出版信息

Dis Esophagus. 2007;20(1):63-8. doi: 10.1111/j.1442-2050.2007.00631.x.

Abstract

It has been suggested that dysphagia is less common after partial versus complete fundoplication. The mechanisms contributing to postoperative dysphagia remain unclear. The objective of the present prospective study was to investigate esophageal motility and the prevalence of dysphagia in patients who have undergone laparoscopic partial fundoplication. Symptoms, lower esophageal sphincter (LES) characteristics and esophageal body motility were evaluated prospectively in 62 patients before and after laparoscopic partial fundoplication: 33 women and 29 men with a mean age of 44 +/- 1.5 years (range, 21-71). The patients filled in symptom questionnaires and underwent stationary and ambulatory manometry and 24-h pH-metry before and after operation. A small but significant increase in LES pressure from 14.8 +/- 0.9 to 17.8 +/- 0.8 mmHg was seen after laparoscopic partial fundoplication. Further, LES characteristics and esophageal body motility were not different post- versus preoperation. Three months after surgery, dysphagia was present in eight patients. No differences in LES characteristics or body motility were present between patients with and without dysphagia. Six months after the operation dysphagia was present in only three patients (3.2% mild and 1.6% severe dysphagia). Adequate reflux control was obtained in 85% of the patients. Laparoscopic partial fundoplication offers adequate reflux control without affecting esophageal body motility and with a very low incidence of postoperative dysphagia.

摘要

有人提出,与完全胃底折叠术相比,部分胃底折叠术后吞咽困难较少见。导致术后吞咽困难的机制仍不清楚。本前瞻性研究的目的是调查接受腹腔镜部分胃底折叠术患者的食管动力和吞咽困难的发生率。对62例患者在腹腔镜部分胃底折叠术前后进行了前瞻性症状、食管下括约肌(LES)特征和食管体部动力评估:33例女性和29例男性,平均年龄44±1.5岁(范围21 - 71岁)。患者在手术前后填写症状问卷,并接受静态和动态测压以及24小时pH监测。腹腔镜部分胃底折叠术后LES压力从14.8±0.9 mmHg小幅但显著增加至17.8±0.8 mmHg。此外,术后LES特征和食管体部动力与术前无差异。术后3个月,8例患者出现吞咽困难。有吞咽困难和无吞咽困难的患者之间LES特征或体部动力无差异。术后6个月,仅3例患者出现吞咽困难(3.2%为轻度,1.6%为重度吞咽困难)。85%的患者获得了充分的反流控制。腹腔镜部分胃底折叠术能提供充分的反流控制,不影响食管体部动力,且术后吞咽困难发生率极低。

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