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[基于海勒文的生物活性组合物在治疗胸膜脓胸中的应用]

[Biologically active helevin-based compositions in the treatment of pleural empyema].

作者信息

Vishnevskiĭ A A, Adamian A A, Akylbekov I K, Romashov Iu V, Supoev A A

出版信息

Khirurgiia (Mosk). 1991 Jun(6):109-11.

PMID:1722835
Abstract

The article analyses the method of topical open treatment of postoperative pyothorax in 17 patients with the use of biologically active helevin-based compositions. The control group was made up of 11 patients with a similar suppurative process who received topical treatment by the same method but with the use of ointments with antibiotics and antiseptics on a fat base. With the use of biologically active compositions (BAC) on a helevin-base, the empyema cavity was completely freed from the pyonecrotic masses and its walls filled with granulation tissue on day 7 of treatment. In the control group the cavity was completely cleansed only on day 19 of treatment. It is shown that BAC possesses a high antibacterial effect not only due to the antibacterial components but because it is based on the laws of physical antiseptics.

摘要

本文分析了17例术后脓胸患者使用基于生物活性海勒文的组合物进行局部开放治疗的方法。对照组由11例患有类似化脓性病变的患者组成,他们采用相同的方法进行局部治疗,但使用的是脂肪基质的含抗生素和防腐剂的软膏。使用基于海勒文的生物活性组合物(BAC)治疗7天时,脓腔中的脓性坏死物质完全清除,腔壁充满肉芽组织。对照组直到治疗第19天脓腔才完全清洁。结果表明,BAC不仅因其抗菌成分具有高抗菌效果,还因为它基于物理防腐原理。

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