哺乳动物磷酸化离子驱动ATP酶
Mammalian phosphorylating ion-motive ATPases.
作者信息
Sachs G, Munson K
机构信息
University of California Los Angeles.
出版信息
Curr Opin Cell Biol. 1991 Aug;3(4):685-94. doi: 10.1016/0955-0674(91)90042-w.
PMID:1722984
Abstract
The pumps discussed in this review are three members of the phosphorylating class of ion transport ATPases. They are the Na(+)-K(+)-, Ca(2+)- and H(+)-K(+)-ATPases. Recent work on their topology, possible transport mechanisms, ion-binding sites and role of the different subunits found for the Na(+)-K(+)- and H(+)-K(+)-ATPases is presented, with a suggestion of a unifying 10-membrane segment model for the catalytic subunit of this class of enzyme.
摘要
本综述中讨论的泵是离子转运ATP酶磷酸化类别的三个成员。它们是钠钾ATP酶、钙ATP酶和氢钾ATP酶。本文介绍了关于钠钾ATP酶和氢钾ATP酶的拓扑结构、可能的转运机制、离子结合位点以及不同亚基作用的最新研究成果，并提出了这类酶催化亚基的统一10膜段模型。
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