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腮腺基底细胞腺瘤的细针穿刺细胞学检查:特征性细胞学表现及诊断陷阱

Fine-needle aspiration cytology of basal cell adenoma of the parotid gland: characteristic cytological features and diagnostic pitfalls.

作者信息

Kawahara Akihiko, Harada Hiroshi, Akiba Jun, Yokoyama Toshiro, Kage Masayoshi

机构信息

Department of Pathology, Kurume University Hospital, Japan.

出版信息

Diagn Cytopathol. 2007 Feb;35(2):85-90. doi: 10.1002/dc.20598.

Abstract

We retrospectively studied the cytological features of aspiration cytology in 12 cases of basal cell adenoma (BCA) and 5 cases mistakenly diagnosed as BCA. On macroscopic findings, the 12 cases of BCA included 7 cases of solid type and 5 cases of cystic type. The characteristic cytological features of solid type BCA were three-dimensional clusters in 71%, sharp-angle small clusters in 86%, basement membrane- like material in 71%, and cell crush in 86%. In contrast, 3 of the 5 cystic type BCA cases showed inadequate cellular components or no basaloid tumor cells, and the cytological diagnosis of BCA could not be determined. In the 5 cases misdiagnosed as BCA, there were 2 cases of pleomorphic adenoma, 2 cases of benign lymphoepithelial cyst, and 1 case of basal cell adenocarcinoma. Accurate differential cytological diagnosis of BCA is relatively easy to determine the solid type BCA, but is more difficult for cystic type BCA.

摘要

我们回顾性研究了12例基底细胞腺瘤(BCA)及5例误诊为BCA的病例的细针穿刺细胞学特征。大体检查发现,12例BCA中,实性型7例,囊性型5例。实性型BCA的特征性细胞学表现为:三维细胞团占71%,锐角形小细胞团占86%,基底膜样物质占71%,细胞挤压征占86%。相比之下,5例囊性型BCA中有3例细胞成分不足或未见基底样肿瘤细胞,无法做出BCA的细胞学诊断。在5例误诊为BCA的病例中,多形性腺瘤2例,良性淋巴上皮囊肿2例,基底细胞腺癌1例。BCA的准确鉴别细胞学诊断对于实性型BCA相对容易确定,但对于囊性型BCA则更困难。

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