DNA疫苗：近期的技术与临床进展
DNA vaccines: recent technological and clinical advances.
作者信息
Ulmer Jeffrey B, Wahren Britta, Liu Margaret A
机构信息
Novartis Vaccines, Emeryville, CA 94608, USA.
出版信息
Discov Med. 2006 Jun;6(33):109-12.
PMID:17234144
Abstract
DNA vaccines generate both T cell and B cell (or antibody) mediated immunities. Methods such as prime-boost regimens and the use of adjuvants in combination with the DNA vaccine have enhanced the therapeutic effectiveness of DNA vaccines in the treatment of cancer, infectious diseases, autoimmune diseases, asthma, and other conditions.
摘要
DNA疫苗可产生T细胞和B细胞（或抗体）介导的免疫反应。诸如初免-加强方案以及将佐剂与DNA疫苗联合使用等方法，提高了DNA疫苗在治疗癌症、传染病、自身免疫性疾病、哮喘及其他病症方面的治疗效果。
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