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在丙泊酚-瑞芬太尼麻醉下,对神经肌肉型和特发性脊柱侧弯患者进行脊柱手术时的皮质体感诱发电位

Cortical somatosensory-evoked potentials during spine surgery in patients with neuromuscular and idiopathic scoliosis under propofol-remifentanil anaesthesia.

作者信息

Hermanns H, Lipfert P, Meier S, Jetzek-Zader M, Krauspe R, Stevens M F

机构信息

Department of Anaesthesiology, University of Duesseldorf, Duesseldorf, Germany.

出版信息

Br J Anaesth. 2007 Mar;98(3):362-5. doi: 10.1093/bja/ael365. Epub 2007 Jan 19.

Abstract

BACKGROUND

Intraoperative monitoring of the spinal cord via cortical somatosensory-evoked potentials (SSEP) is a routine during spinal surgery. However, especially in neuromuscular scoliosis, the reliability of cortical SSEP has been questioned. Therefore, we compared the feasibility of cortical SSEP in idiopathic and neuromuscular scoliosis using anaesthetics known to have only minimal effect on SSEP recordings.

METHODS

Total intravenous anaesthesia with propofol and remifentanil as continuous infusion was standardized for all the patients. Median and tibial nerve cortical SSEP were monitored in 54 patients who underwent surgery for spinal deformity. Twenty-seven had idiopathic scoliosis and 27 had neuromuscular scoliosis. The portion of reproducible results and intraoperative changes were compared between the groups.

RESULTS

In both groups, cortical SSEP could be monitored with sufficient reliability. Only in two patients with idiopathic and four patients with neuromuscular scoliosis no reproducible traces could be obtained. The amplitudes in patients with neuromuscular scoliosis were lower than in those with idiopathic scoliosis, but not statistically significant. There were no postoperative neurological deficits. The number of false positive and true positive did not differ between the groups.

CONCLUSIONS

Assessment of cortical SSEP during spine surgery was equally effective and reliable in patients with neuromuscular scoliosis and in patients with idiopathic scoliosis, possibly as a result of propofol-remifentanil anaesthesia.

摘要

背景

在脊柱手术中,通过皮层体感诱发电位(SSEP)对脊髓进行术中监测是一项常规操作。然而,尤其是在神经肌肉型脊柱侧弯中,皮层SSEP的可靠性受到了质疑。因此,我们使用已知对SSEP记录影响极小的麻醉剂,比较了皮层SSEP在特发性和神经肌肉型脊柱侧弯中的可行性。

方法

所有患者均采用丙泊酚和瑞芬太尼持续输注的全静脉麻醉。对54例接受脊柱畸形手术的患者监测了正中神经和胫神经皮层SSEP。其中27例为特发性脊柱侧弯,27例为神经肌肉型脊柱侧弯。比较两组间可重复结果的比例和术中变化。

结果

两组中,皮层SSEP均可得到足够可靠的监测。仅2例特发性脊柱侧弯患者和4例神经肌肉型脊柱侧弯患者未获得可重复的波形。神经肌肉型脊柱侧弯患者的波幅低于特发性脊柱侧弯患者,但差异无统计学意义。术后无神经功能缺损。两组间假阳性和真阳性的数量无差异。

结论

在脊柱手术中,对神经肌肉型脊柱侧弯患者和特发性脊柱侧弯患者进行皮层SSEP评估同样有效且可靠,这可能是丙泊酚-瑞芬太尼麻醉的结果。

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