Rawlings Nigel G, Brownstein Seymour, Robinson Jennifer W, Jordan David R
Department of Ophthalmology, University of Ottawa Eye Institute, The Ottawa Hospital, Ottawa, Ontario, Canada.
Ophthalmic Plast Reconstr Surg. 2007 Jan-Feb;23(1):79-80. doi: 10.1097/IOP.0b013e31802c7e6e.
A 40-year-old woman with an orbital lesion presented with a history of slowly progressive proptosis. A thorough systemic workup did not reveal any stigmata of multiple myeloma, and she was treated with a course of orbital radiotherapy. Histopathologic studies of the biopsy specimen revealed a proliferation of neoplastic plasma cells, which produced monoclonal lambda light chains surrounding concretions of congophilic, amorphous material. The lesion was diagnosed as a solitary osseous plasmacytoma of the orbit containing amyloid.
一名患有眼眶病变的40岁女性，有缓慢进展性眼球突出病史。全面的系统检查未发现多发性骨髓瘤的任何体征，她接受了一个疗程的眼眶放射治疗。活检标本的组织病理学研究显示肿瘤性浆细胞增生，产生单克隆λ轻链，围绕嗜刚果红的无定形物质凝块。该病变被诊断为眼眶孤立性骨浆细胞瘤伴淀粉样变。
