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男性膀胱过度活动症:尿动力学及抗胆碱能药物的作用

Male overactive bladder: the role of urodynamics and anticholinergics.

作者信息

MacDiarmid Scott, Rogers Alexandra

机构信息

Alliance Urology Specialists, Bladder Control and Pelvic Pain Center, 509 N. Elam, Greensboro, NC 27403, USA.

出版信息

Curr Urol Rep. 2007 Jan;8(1):66-73. doi: 10.1007/s11934-007-0023-7.

Abstract

Millions of men suffer from overactive bladder and lower urinary tract symptoms. The adverse effects on quality of life and costs associated with the condition have been well described. In men, the pathophysiology of lower urinary tract symptoms may be from a number of causes including bladder outlet obstruction, detrusor overactivity, or both. Increasing data and clinical experience support the efficacy and safety of anticholinergics in men; the rate of urinary retention has been equal to that of placebo in short-term studies. Urodynamics play a vital role in defining the bladder and/or outlet dysfunction and help direct one's therapy.

摘要

数以百万计的男性患有膀胱过度活动症和下尿路症状。这种疾病对生活质量的负面影响以及与之相关的费用已得到充分描述。在男性中,下尿路症状的病理生理学可能由多种原因引起,包括膀胱出口梗阻、逼尿肌过度活动或两者兼而有之。越来越多的数据和临床经验支持抗胆碱能药物在男性中的有效性和安全性;在短期研究中,尿潴留率与安慰剂相当。尿动力学在确定膀胱和/或出口功能障碍方面起着至关重要的作用,并有助于指导治疗。

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