一项关于丙戊酸用于治疗子宫腺肌病的超说明书用药的初步研究。
A pilot study on the off-label use of valproic acid to treat adenomyosis.
作者信息
Liu Xishi, Guo Sun-Wei
机构信息
Department of Gynecology, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
出版信息
Fertil Steril. 2008 Jan;89(1):246-50. doi: 10.1016/j.fertnstert.2006.11.009. Epub 2007 Jan 18.
Abstract
Following on the heels of the discovery that endometriosis is an epigenetic disease, we conducted a pilot study on the off-label use of valproic acid to treat adenomyosis. We found that by the end of the 3-month treatment, all three recruited patients reported complete disappearance of dysmenorrhea, with an average of one-third reduction in uterus size.
摘要
在发现子宫内膜异位症是一种表观遗传疾病之后，我们开展了一项关于丙戊酸治疗子宫腺肌病的非标签使用的试点研究。我们发现，在3个月的治疗结束时，所有三名招募的患者均报告痛经完全消失，子宫大小平均缩小了三分之一。
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