使用偏振调制红外光谱法研究聚乙二醇自组装单分子层的水合作用。

Hydration of oligo(ethylene glycol) self-assembled monolayers studied using polarization modulation infrared spectroscopy.

作者信息

Skoda M W A, Jacobs R M J, Willis J, Schreiber F

机构信息

Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford OX1 3QZ, U.K.

出版信息

Langmuir. 2007 Jan 30;23(3):970-4. doi: 10.1021/la0616653.

DOI:10.1021/la0616653

PMID:17240997

Abstract

The interaction with water of protein-resistant monolayers (SAMs), self-assembled from (triethylene glycol) terminated thiol HS(CH2)11(OCH2CH2)3OMe solutions, was studied using in and ex situ polarization-modulated Fourier transform infrared spectroscopy. In particular, shifts in the position of the characteristic C-O-C stretching vibration were observed after the monolayers had been exposed to water. The shift in frequency increased when the SAM was observed in direct contact with a thin layer of water. It was found that the magnitude of the shift also depended on the surface coverage of the SAM. These findings suggest a rather strong interaction of oligo(ethylene glycol) SAMs with water and indicate the penetration of water into the upper region of the monolayer.

摘要

利用原位和非原位偏振调制傅里叶变换红外光谱法，研究了由（三甘醇）封端的硫醇HS(CH2)11(OCH2CH2)3OMe溶液自组装而成的抗蛋白质单分子层（自组装单分子膜，SAMs）与水的相互作用。特别地，在单分子层暴露于水之后，观察到了特征C-O-C伸缩振动位置的变化。当观察到自组装单分子膜与一薄层水直接接触时，频率变化增大。还发现，变化的幅度也取决于自组装单分子膜的表面覆盖率。这些发现表明，低聚（乙二醇）自组装单分子膜与水之间存在相当强的相互作用，并表明水渗透到了单分子层的上部区域。