Zaterka Schlioma, Eisig Jaime N, Chinzon Decio, Rothstein Wolfgang
Department of Gastroenterology of UNICAMP, São Paulo, Brazil.
Helicobacter. 2007 Feb;12(1):82-8. doi: 10.1111/j.1523-5378.2007.00474.x.
The prevalence of Helicobacter pylori is higher in developing countries. Sanitary facilities, crowding and ethnic group are some of the factors related to H. pylori infection. The aim of this study was to investigate in blood donors, free of dyspeptic symptoms, the prevalence and factors influencing H. pylori infection.
This study was conducted in São Paulo, a city known to have a mixed population coming from all over the country. A total of 1008 blood donors were initially included in the study. After a final revision of all the questionnaires, 993 were included in the final analysis (746 males). H. pylori status was checked by an ELISA test. The following associations to infection were analyzed: sex, age, ethnic group, previous upper gastrointestinal (GI) endoscopy, smoking, alcoholism, drug addiction, type of drinking water, crowding, sanitary facilities, and family income.
Infection was observed in 496 of 746 male (66.5%) and in 156 of 247 female (63.2%) blood donors. Infection prevalence increased according to age group, regardless of sex. Prevalence was lower in White population than in non-White. No relationship was observed between infection and smoking, drug addiction, and alcohol. A positive relation was observed between infection and previous upper GI endoscopy, and type of drinking water, regardless if currently or during childhood. Crowding and lack of toilet in the house during childhood resulted in a higher infection rate. Lower familial income and educational level showed a positive association to infection.
Prevalence of H. pylori is higher in non-White population, independent of gender. A positive association was observed in aging, previous upper GI endoscopy, crowding, type of drinking water, lack of toilet during childhood, lower family income, and lower educational level.
幽门螺杆菌在发展中国家的感染率较高。卫生设施、拥挤程度和种族是与幽门螺杆菌感染相关的一些因素。本研究的目的是调查无消化不良症状的献血者中幽门螺杆菌感染的患病率及其影响因素。
本研究在圣保罗市进行，该市人口来自全国各地，种族混合。共有1008名献血者最初纳入研究。在对所有问卷进行最终修订后，993名（746名男性）纳入最终分析。通过酶联免疫吸附测定（ELISA）检测幽门螺杆菌感染状况。分析了以下与感染的关联因素：性别、年龄、种族、既往上消化道内镜检查史、吸烟、酗酒、药物成瘾、饮用水类型、拥挤程度、卫生设施和家庭收入。
746名男性献血者中有496名（66.5%）感染，247名女性献血者中有156名（63.2%）感染。无论性别，感染患病率均随年龄组增加而升高。白人人群的患病率低于非白人。未观察到感染与吸烟、药物成瘾和饮酒之间的关系。观察到感染与既往上消化道内镜检查史以及饮用水类型（无论当前还是儿童时期）之间存在正相关。儿童时期居住环境拥挤和家中无厕所导致感染率较高。较低的家庭收入和教育水平与感染呈正相关。
幽门螺杆菌在非白人人群中的患病率较高，与性别无关。在年龄增长、既往上消化道内镜检查史、拥挤程度、饮用水类型、儿童时期无厕所、较低的家庭收入和较低的教育水平方面观察到正相关。
