64层螺旋CT延迟强化评估急性再灌注心肌梗死
Assessment of acute reperfused myocardial infarction with delayed enhancement 64-MDCT.
作者信息
Baks Timo, Cademartiri Filippo, Moelker Amber D, van der Giessen Willem J, Krestin Gabriel P, Duncker Dirk J, de Feyter Pim J
机构信息
Department of Cardiology, Erasmus Medical Center, Dr. Molewaterplein 40, Rotterdam, The Netherlands.
出版信息
AJR Am J Roentgenol. 2007 Feb;188(2):W135-7. doi: 10.2214/AJR.05.1176.
OBJECTIVE
The purpose of this study was to evaluate the utility of delayed enhancement 64-MDCT in the assessment of myocardial infarct size in a porcine model of acute reperfused myocardial infarction. CT can be used for noninvasive assessment of coronary artery stenosis, but to our knowledge, evaluation of myocardial viability in the subacute phase of acute myocardial infarction has not been validated. We performed delayed enhancement imaging on six domestic swine 5 days after reperfused acute myocardial infarction and assessed the relation between delayed enhancement patterns in vivo and the extent of viable and nonviable myocardium at postmortem histochemical analysis.
CONCLUSION
Delayed enhancement imaging with 64-MDCT can be used for accurate assessment of the size of reperfused acute myocardial infarcts.
目的
本研究的目的是评估64层螺旋CT延迟强化成像在急性再灌注心肌梗死猪模型中评估心肌梗死面积的效用。CT可用于冠状动脉狭窄的无创评估，但据我们所知，急性心肌梗死亚急性期心肌存活能力的评估尚未得到验证。我们在6只家猪急性心肌梗死后再灌注5天进行延迟强化成像，并在尸检组织化学分析中评估体内延迟强化模式与存活和非存活心肌范围之间的关系。
结论
64层螺旋CT延迟强化成像可用于准确评估再灌注急性心肌梗死的面积。
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