秘鲁献血者中的人类疱疹病毒8型：一个疾病高度流行的人群？

Human herpesvirus-8 in Peruvian blood donors: a population with hyperendemic disease?

作者信息

Mohanna Salim, Portillo Jose-Andres, Carriquiry Gabriela, Vidal Julio, Ferrufino Juan Carlos, Sanchez Juvenal, Bravo Francisco, Gotuzzo Eduardo

机构信息

Human Herpesvirus 8 and Classic Kaposi Sarcoma Working Group, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.

出版信息

Clin Infect Dis. 2007 Feb 15;44(4):558-61. doi: 10.1086/511044. Epub 2007 Jan 11.

DOI:10.1086/511044

PMID:17243060

Abstract

Serum samples from 128 blood donors were tested for antibodies specific for human herpesvirus-8 by an immunofluorescence assay that detects antibodies against mainly lytic antigens. An overall seroprevalence of 56.25% was found (male donors, 54.68%; female donors, 57.11%). These findings indicate that human herpesvirus-8 infection is hyperendemic in Peruvian blood donors.

摘要

通过一种主要检测针对裂解抗原抗体的免疫荧光测定法，对128名献血者的血清样本进行了人类疱疹病毒8型特异性抗体检测。总体血清阳性率为56.25%（男性献血者为54.68%；女性献血者为57.11%）。这些发现表明，人类疱疹病毒8型感染在秘鲁献血者中呈高度地方性流行。