van Wuijckhuise L, Snoep J, Cremers G, Duvivier A, Groeneveld A, Ottens W, van der Sar S
GD, Deventer.
Tijdschr Diergeneeskd. 2006 Dec 1;131(23):858-61.
Between mid September and the beginning of November 2005, the Animal Health Service (AHS) received thirteen reports offarms on which several animals showed severe symptoms of solar eczema. Blood chemistry showed very high levels of GOT/AST and GGT indicative of severe liver damage. Farm visits to eight farms showed that the animals--previous to the start of the symptoms--had been grazing 24 hours/day and received no additional feed. Ingestion of poisonous plants or medications was considered unlikely to have caused the liver damage, and liver fluke infections were present on only two farms. Microscopic examination of specimens of grass revealed the presence of spores of Pithomyces chartarum in samples taken from six of nine farms. This fungus produces the mycotoxin sporidesmin, which causes severe liver damage and pithomycotoxicosis (facial eczema). This article is the first to describe Pithomyces chartarum in cattle in mainland Europe. Further research on the distribution and re-occurrence of Pithomyces chartarum infection and sporidesmin survival in grass silage is recommended.
2005年9月中旬至11月初，动物卫生服务局（AHS）收到13份关于农场的报告，报告称有几只动物出现了严重的日光性湿疹症状。血液化学检测显示谷草转氨酶（GOT/AST）和γ-谷氨酰转移酶（GGT）水平非常高，表明肝脏受到严重损伤。对8个农场的实地走访发现，这些动物在症状出现之前每天24小时都在放牧，没有额外喂食。摄入有毒植物或药物不太可能导致肝脏损伤，只有两个农场存在肝片吸虫感染。对草样本的显微镜检查发现，从9个农场中的6个农场采集的样本中存在稻梨孢菌的孢子。这种真菌会产生霉菌毒素孢霉毒素，可导致严重的肝脏损伤和霉毒素中毒（面部湿疹）。本文首次描述了欧洲大陆牛体内的稻梨孢菌。建议对稻梨孢菌感染的分布和复发情况以及孢霉毒素在青贮饲料中的存活情况进行进一步研究。
