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[关于阿司匹林在女性心血管疾病一级预防中应用的现代观点]

[The modern view on the use of aspirin for the primary prophylaxis of cardiovascular diseases in women].

作者信息

Zakharov O V, Arablinskiĭ A V

出版信息

Klin Med (Mosk). 2006;84(11):10-5.

PMID:17243603
Abstract

Cardiovascular diseases (CVD) occupy the first place in the world among all causes of disability and death. Aspirin is an effective antithrombocyte agent, the efficiency and safety of which has been demonstrated by numerous studies. Despite its high effectiveness in treatment of acute myocardial infarction and secondary prophylaxis of CVD both in men and women, the use of aspirin for primary prophylaxis is still questionable. Presently, the appropriateness of aspirin application as a means of primary prevention of CVD in women older than 45 has not been clarified yet. The present article discusses this question.

摘要

心血管疾病(CVD)在全球所有致残和致死原因中位居首位。阿司匹林是一种有效的抗血小板药物,众多研究已证实其有效性和安全性。尽管阿司匹林在治疗急性心肌梗死以及男女心血管疾病的二级预防方面具有高效性,但将其用于一级预防仍存在疑问。目前,对于45岁以上女性使用阿司匹林作为心血管疾病一级预防手段的合理性尚未明确。本文将探讨这一问题。

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