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经巩膜红激光睫状体光凝联合局限性视网膜前冷凝术治疗新生血管性青光眼

Transscleral red-laser cyclophotocoagulation combined with limited anterior retinal cryocoagulation in neovascular glaucoma.

作者信息

Raivio Virpi E, Immonen Ilkka J R, Puska Päivi M

机构信息

Helsinki University Eye Hospital, Helsinki, Finland.

出版信息

Acta Ophthalmol Scand. 2007 Feb;85(1):60-6. doi: 10.1111/j.1600-0420.2006.00746.x.

Abstract

PURPOSE

To evaluate transscleral contact red-laser cyclophotocoagulation (CPC), using a visible red 647-nm krypton or 670-nm diode laser and limited transscleral anterior retinal cryocoagulation in neovascular glaucoma.

METHODS

In a retrospective case series, 35 eyes of 35 consecutive patients treated during a period of 6 years were included in the study. Inclusion was dependent on follow-up of at least 1 month. Patients who had undergone previous cyclodestructive procedures and patients who received an additional glaucoma operation in conjunction with CPC were excluded. In the combined procedure, the power per CPC application was 370-450 mW and exposure time was 10 seconds. One to two rows of cryoapplications were given to 360 degrees of the anterior retina.

RESULTS

The success rate in terms of intraocular pressure (IOP of 8-21 mmHg or a decrease in IOP > 30%) was 89% at the last follow-up (17 +/- 15 months). Iris neovascularization regressed in 51% of eyes. Hypotonia developed in one (3%) eye (IOP of 5 mmHg). No cases of phthisis bulbi were seen. Visual acuity (VA) declined in 49% of eyes.

CONCLUSIONS

A combination of transscleral contact red-laser CPC with limited anterior retinal cryocoagulation is efficient in lowering IOP in neovascular glaucoma and is well tolerated. During follow-up, a decrease in VA occurs in a significant proportion of patients.

摘要

目的

使用可见红光647纳米氪激光或670纳米二极管激光经巩膜接触式红色激光睫状体光凝术(CPC)以及有限的经巩膜视网膜前部冷冻疗法,评估其在新生血管性青光眼中的应用效果。

方法

在一项回顾性病例系列研究中,纳入了6年间连续治疗的35例患者的35只眼。纳入标准为至少随访1个月。排除既往接受过睫状体破坏手术的患者以及在CPC治疗的同时还接受了其他青光眼手术的患者。在联合手术中,每次CPC治疗的功率为370 - 450毫瓦,曝光时间为10秒。对视网膜前部360度进行1至2排冷冻治疗。

结果

在最后一次随访时(17±15个月),眼压(眼压为8 - 21 mmHg或眼压降低> 30%)的成功率为89%。51%的患眼中虹膜新生血管消退。1只眼(3%)出现低眼压(眼压为5 mmHg)。未观察到眼球痨病例。49%的患眼视力下降。

结论

经巩膜接触式红色激光CPC联合有限的视网膜前部冷冻疗法在降低新生血管性青光眼的眼压方面有效,且耐受性良好。在随访期间,相当比例的患者视力下降。

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