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药物洗脱支架植入术后早期再狭窄:血小板活化的潜在作用。

Early restenosis after drug-eluting stent implantation: A putative role for platelet activation.

作者信息

Tamburino Corrado, Ussia Gian Paolo, Zimarino Marco, Galassi Alfredo R, De Caterina Raffaele

机构信息

Institute of Cardiology, Ferrarotto Hospital, University of Catania, Italy.

出版信息

Can J Cardiol. 2007 Jan;23(1):57-9. doi: 10.1016/s0828-282x(07)70214-3.

DOI:10.1016/s0828-282x(07)70214-3
PMID:17245484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2649173/
Abstract

Drug-eluting stents (DES) reduce intimal hyperplasia and restenosis, but they also inhibit stent endothelization, making the vascular surface more thrombogenic. The present report describes two cases of in-stent restenosis after DES deployment at exactly the same sites where subacute stent thrombosis had occurred. Extremely careful follow-up is mandatory after the recognition of intraluminal thrombi inside DES because restenosis may occur at the same site of DES thrombosis.

摘要

药物洗脱支架(DES)可减少内膜增生和再狭窄,但它们也会抑制支架内皮化,使血管表面更易形成血栓。本报告描述了两例DES置入后在亚急性支架血栓形成的完全相同部位发生支架内再狭窄的病例。在识别出DES内的腔内血栓后,必须进行极其仔细的随访,因为再狭窄可能发生在DES血栓形成的同一部位。

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Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents.药物洗脱支架成功植入后血栓形成的发生率、预测因素及转归
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Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.雷帕霉素洗脱支架与标准支架治疗冠状动脉狭窄患者的比较
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Impact of cilostazol on restenosis after percutaneous coronary balloon angioplasty.西洛他唑对经皮冠状动脉球囊血管成形术后再狭窄的影响。
Circulation. 1999 Jul 6;100(1):21-6. doi: 10.1161/01.cir.100.1.21.
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Inhibition of intimal thickening after balloon angioplasty in porcine coronary arteries by targeting regulators of the cell cycle.通过靶向细胞周期调节因子抑制猪冠状动脉球囊血管成形术后内膜增厚。
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Randomised comparison of implantation of heparin-coated stents with balloon angioplasty in selected patients with coronary artery disease (Benestent II).肝素涂层支架植入术与球囊血管成形术在特定冠心病患者中的随机对照研究(贝内斯特 II 试验)
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