Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH England.
Genetics. 1983 Jan;103(1):43-64. doi: 10.1093/genetics/103.1.43.
Mating behavior in adult male nematodes can be assayed by mating efficiency, i.e., the number of cross progeny sired by males under standard conditions. Mutant males from 220 strains, representing most of the known complementation groups of C. elegans, have been examined for mating efficiency and for anatomical abnormalities of the specialized male copulatory organs. These data extend the phenotypic description of these mutants and indicate what anatomical and behavioral components are necessary for the ability to mate successfully. Also, mutants with specific defects in the male were sought by establishing superficially wild-type hermaphrodite stocks after mutagenesis and testing the males segregated by these stocks for mating efficiency. Forty-nine of 1119 stocks yielded abnormal males. Seventeen were characterized in detail and found to be abnormal in sensory behavior (carrying mutations in the genes che-2 or che-3) or male genital anatomy (carrying mutations in one of the genes mab-1 to mab-10). Four of the mab (male abnormal) genes affect specific postembryonic cell lineages.
成年雄性线虫的交配行为可以通过交配效率来检测，即在标准条件下雄性产生异配后代的数量。对来自 220 个品系的突变雄性进行了交配效率和专门的雄性交配器官解剖异常的检查，这些品系代表了大多数已知的秀丽隐杆线虫的互补群。这些数据扩展了这些突变体的表型描述，并指出了成功交配所需的解剖和行为成分。此外，通过诱变建立表面上野生型雌雄同体品系，并测试这些品系分离出的雄性的交配效率，寻找具有特定雄性缺陷的突变体。在 1119 个品系中，有 49 个产生了异常雄性。对其中的 17 个进行了详细描述，发现它们在感觉行为（携带 che-2 或 che-3 基因的突变）或雄性生殖器解剖结构（携带 mab-1 至 mab-10 基因之一的突变）方面异常。mab（雄性异常）基因中的 4 个影响特定的胚胎后细胞谱系。
