Department of Zoology, University of Oklahoma, Norman, Oklahoma 73019.
Genetics. 1984 Oct;108(2):409-24. doi: 10.1093/genetics/108.2.409.
The chromosomal architecture of genotype x environment interactions was investigated in lines of Drosophila melanogaster selected for increased or decreased sternopleural bristle number at 18 degrees , 25 degrees and 29 degrees . In general, interactions were found to have a stabilizing effect upon the bristle phenotype, in the sense that the genotype x environment interaction tended to increase bristle number under conditions in which temperature alone reduced bristle number and vice versa. The polygenic modifiers of mean bristle number were often separable from modifiers of the response to temperature both at the chromosomal level and intrachromosomally. In one of the low selection lines, a temperature-dependent polygenic locus was mapped on chromosome 3. It is suggested that genotype x environment interactions be thought of in terms of conditional polygenic expression. Such conditionality may be one of the ways in which polygenic variation is maintained in a population in the face of selection for an optimum phenotype.
研究了在 18 度、25 度和 29 度下选择增加或减少果蝇前胸刚毛数的品系中基因型与环境互作的染色体结构。一般来说，相互作用对刚毛表型有稳定作用，因为在温度单独降低刚毛数的情况下，基因型与环境的相互作用往往会增加刚毛数，反之亦然。平均刚毛数的多基因修饰因子往往可以与温度反应的修饰因子在染色体水平和染色体内部分离。在低选择系之一中，一个温度依赖的多基因座被定位在 3 号染色体上。有人认为，基因型与环境的相互作用可以用条件多基因表达来考虑。这种条件性可能是多基因变异在面对最优表型选择时在种群中得以维持的方式之一。
