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The design of ALLHAT may have biased the study's outcome in favor of the diuretic cohort.

作者信息

Hebert Lee A, Rovin Brad H, Hebert Christopher J

机构信息

Ohio State University Medical Center, 1654 Upham Drive, Columbus, OH 43210, USA.

出版信息

Nat Clin Pract Nephrol. 2007 Feb;3(2):60-1. doi: 10.1038/ncpneph0391.

DOI:10.1038/ncpneph0391
PMID:17251990
Abstract
摘要

相似文献

1
The design of ALLHAT may have biased the study's outcome in favor of the diuretic cohort.
Nat Clin Pract Nephrol. 2007 Feb;3(2):60-1. doi: 10.1038/ncpneph0391.
2
LIFE and SCOPE: what guidance do they offer alongside ALLHAT and ANBP2?生活与范围:与抗高血压和降脂治疗预防心脏病发作试验(ALLHAT)及澳大利亚国家血压研究(ANBP2)相比,它们提供了哪些指导?
J Hum Hypertens. 2004 May;18(5):295-300. doi: 10.1038/sj.jhh.1001675.
3
ALLHAT: a saga of missed opportunities.
J Hum Hypertens. 2003 Jun;17(6):373-7. doi: 10.1038/sj.jhh.1001564.
4
The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT): ALL predictable, and no big surprise out of a HAT?
J Hum Hypertens. 2003 Jun;17(6):367-72. doi: 10.1038/sj.jhh.1001556.
5
A family physician questions the conclusions from ALLHAT.一位家庭医生对抗高血压和降脂治疗预防心脏病发作试验(ALLHAT)的结论提出质疑。
Am J Hypertens. 2004 Apr;17(4):361-5. doi: 10.1016/j.amjhyper.2003.11.011.
6
ALLHAT in perspective: implications to clinical practice and clinical trials.从ALLHAT看问题:对临床实践和临床试验的启示
Med J Malaysia. 2005 Jun;60(2):239-45.
7
The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack (ALLHAT) Trial: focus on the diabetic patient.预防心脏病发作的降压和降脂治疗(ALLHAT)试验:聚焦糖尿病患者。
Curr Hypertens Rep. 2004 Jun;6(3):212-4.
8
[After the ALLHAT trial, what do we know about treatment for hypertension that we did not know before?].
Rev Esp Cardiol. 2003 Jul;56(7):642-8.
9
[What did the ALLHAT study bring? To do the one without foregoing the other].
MMW Fortschr Med. 2003 Dec 18;145(51-52):36-7.
10
ALLHAT: definitive answers or continuing uncertainty?抗高血压和降脂治疗预防心脏病发作试验(ALLHAT):最终答案还是持续的不确定性?
J Renin Angiotensin Aldosterone Syst. 2003 Mar;4(1):3-5. doi: 10.3317/jraas.2003.004.

引用本文的文献

1
Diuretics: a review of the pharmacology and effects on glucose homeostasis.利尿剂:药理学及其对葡萄糖稳态影响的综述
Front Pharmacol. 2025 Mar 28;16:1513125. doi: 10.3389/fphar.2025.1513125. eCollection 2025.
2
Diuretics prevent Rho-kinase activation and expression of profibrotic/oxidative genes in the hypertensive aortic wall.利尿剂可预防高血压主动脉壁中 Rho 激酶的激活以及促纤维化/氧化基因的表达。
Ther Adv Cardiovasc Dis. 2016 Dec;10(6):338-347. doi: 10.1177/1753944716666208. Epub 2016 Sep 1.
3
Is fluid overload as measured by bioimpedance spectroscopy harmful in CKD-if so, why?
通过生物电阻抗光谱法测量的液体超负荷在慢性肾脏病中是否有害——如果有害,原因是什么?
Clin J Am Soc Nephrol. 2015 Jan 7;10(1):1-3. doi: 10.2215/CJN.11311114. Epub 2014 Dec 15.
4
Do thiazides worsen metabolic syndrome and renal disease? The pivotal roles for hyperuricemia and hypokalemia.噻嗪类药物会加重代谢综合征和肾脏疾病吗?高尿酸血症和低钾血症的关键作用。
Curr Opin Nephrol Hypertens. 2008 Sep;17(5):470-6. doi: 10.1097/MNH.0b013e328305b9a5.