Tom Sabrina M, Fox Craig R, Trepel Christopher, Poldrack Russell A
Department of Psychology, University of California Los Angeles (UCLA), Franz Hall, Box 951563, Los Angeles, CA 90095-1563, USA.
Science. 2007 Jan 26;315(5811):515-8. doi: 10.1126/science.1134239.
People typically exhibit greater sensitivity to losses than to equivalent gains when making decisions. We investigated neural correlates of loss aversion while individuals decided whether to accept or reject gambles that offered a 50/50 chance of gaining or losing money. A broad set of areas (including midbrain dopaminergic regions and their targets) showed increasing activity as potential gains increased. Potential losses were represented by decreasing activity in several of these same gain-sensitive areas. Finally, individual differences in behavioral loss aversion were predicted by a measure of neural loss aversion in several regions, including the ventral striatum and prefrontal cortex.
人们在做决策时通常对损失比对同等收益表现出更高的敏感度。我们在个体决定是否接受提供50/50输赢机会的赌博时，研究了损失厌恶的神经关联。随着潜在收益增加，一系列广泛的区域（包括中脑多巴胺能区域及其靶点）显示出活动增加。潜在损失则通过这些对收益敏感的相同区域中几个区域的活动减少来体现。最后，包括腹侧纹状体和前额叶皮层在内的几个区域的神经损失厌恶指标预测了行为损失厌恶的个体差异。
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