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用于治疗胸主动脉瘤的“冰冻象鼻”技术

The frozen elephant trunk technique for treatment of thoracic aortic aneurysms.

作者信息

Baraki Hassina, Hagl Christian, Khaladj Narwid, Kallenbach Klaus, Weidemann Jürgen, Haverich Axel, Karck Matthias

机构信息

Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany.

出版信息

Ann Thorac Surg. 2007 Feb;83(2):S819-23; discussion S824-31. doi: 10.1016/j.athoracsur.2006.10.083.

Abstract

BACKGROUND

The frozen elephant trunk technique allows for single-stage repair of combined aortic arch and descending aortic aneurysms using a hybrid prosthesis with a stented and a nonstented end. This report summarizes the operative and follow-up data (mean follow-up: 20 months) with this new treatment.

METHODS

Between September 2001 and March 2006, 39 patients (15 women; mean age, 62 years) were operated on after approval by the local Institutional Review Board. Indications for operation were aneurysms in 18 patients and aortic dissections in 21. The stented end of the hybrid prosthesis was placed through the opened aortic arch under fluoroscopic control using hypothermic circulatory arrest and selective antegrade cerebral perfusion.

RESULTS

All patients survived the procedure. Five patients (12.8%) died early postoperatively, with two deaths directly related to the procedure. Symptoms of neurologic dysfunction developed in 5 patients and resolved completely in 2. In 1 patient, the descending aorta was perforated owing to misplacement of the stented end of the hybrid prosthesis. In 23 of 25 patients with postoperative computed tomography imaging (>6 months postoperatively), complete thrombus formation around the frozen elephant trunk was observed.

CONCLUSIONS

This procedure is performed through a median sternotomy and combines the concepts of the elephant trunk principle and endovascular stenting of descending aortic aneurysms. Favorable intraoperative and postoperative results in the follow-up with thrombus formation around the stented descending aortic segment has encouraged us to evaluate all patients with thoracic aneurysms extending proximal and distal of the left subclavian artery for this treatment.

摘要

背景

冷冻象鼻技术允许使用一种带有支架端和无支架端的混合假体对主动脉弓和降主动脉瘤进行一期修复。本报告总结了采用这种新治疗方法的手术及随访数据(平均随访时间:20个月)。

方法

在2001年9月至2006年3月期间,经当地机构审查委员会批准,对39例患者(15例女性;平均年龄62岁)进行了手术。手术指征为18例动脉瘤患者和21例主动脉夹层患者。在低温循环停止和选择性顺行脑灌注的情况下,在透视引导下通过开放的主动脉弓放置混合假体的支架端。

结果

所有患者均顺利完成手术。5例患者(12.8%)术后早期死亡,其中2例死亡与手术直接相关。5例患者出现神经功能障碍症状,2例完全恢复。1例患者因混合假体支架端放置错误导致降主动脉穿孔。在25例术后进行计算机断层扫描成像的患者中(术后>6个月),23例观察到冷冻象鼻周围完全形成血栓。

结论

该手术通过正中胸骨切开术进行,结合了象鼻原理和降主动脉瘤血管内支架置入的概念。在随访中,支架置入的降主动脉段周围形成血栓,术中及术后结果良好,这促使我们对所有左锁骨下动脉近端和远端均有动脉瘤的患者评估采用这种治疗方法。

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