Martino Davide, Defazio Giovanni, Abbruzzese Giovanni, Marchese Roberta, Fabbrini Giovanni, Decembrino Venturino, Berardelli Alfredo
Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy.
Mov Disord. 2007 Mar 15;22(4):576-8. doi: 10.1002/mds.21322.
We previously observed that diseases of the anterior ocular segment predispose to primary blepharospasm, but not to other focal dystonias. In this multicenter study, we tested whether prior scoliosis, which increases the risk of developing cervical dystonia, is also a predisposing factor to blepharospasm. The frequency of scoliosis did not differ between blepharospasm patients and controls. This finding supports the hypothesis that environmental risk factors may be specific for a single form of adult-onset dystonia.
我们之前观察到眼前节疾病易引发原发性睑痉挛,但不会引发其他局灶性肌张力障碍。在这项多中心研究中,我们测试了先前的脊柱侧弯(这种情况会增加患颈部肌张力障碍的风险)是否也是睑痉挛的诱发因素。睑痉挛患者和对照组之间脊柱侧弯的发生率并无差异。这一发现支持了以下假说,即环境风险因素可能针对单一形式的成人起病肌张力障碍具有特异性。