Podobnik M, Singer Z, Bulić M, Kukura V, Ciglar S
Department of Obstetrics and Gynecology, University Hospital Ozren Novosel, Zagreb, Croatia.
J Perinat Med. 1991;19(6):455-63. doi: 10.1515/jpme.1991.19.6.455.
Transabdominal placental biopsy under ultrasound guidance was carried out in 260 cases in the second trimester and 50 cases in the third trimester of pregnancy. Placental tissue was aspirated using an 18 or 20 gauge needle. In a total of 310 placental biopsies in the second and third trimester, 100 were performed because of suspicious ultrasonographic findings. Placental biopsy is simple in the presence of severe oligohydramnios where fetal blood sampling is usually more difficult. Oligohydramnios and polyhydramnios were the ultrasonographic findings in 50% of cases and were found to be associated with 30% of abnormal chromosomal findings. There was one (0.3%) abortion within two weeks following placental biopsy. Placental biopsy did not affect the outcome of the pregnancy.
在超声引导下对260例孕中期孕妇及50例孕晚期孕妇进行经腹胎盘活检。使用18号或20号针头抽取胎盘组织。在孕中期和孕晚期总共310例胎盘活检中，100例是由于超声检查结果可疑而进行的。在严重羊水过少的情况下，胎盘活检操作简单，而胎儿采血通常更困难。羊水过少和羊水过多是50%病例的超声检查结果，并且发现与30%的染色体异常结果相关。胎盘活检后两周内发生1例（0.3%）流产。胎盘活检不影响妊娠结局。
