Nakase H, Sakaki T, Fujita T, Tsunoda S, Nakamura M, Imai T, Hiasa Y
Department of Neurosurgery, Nara Medical University, Japan.
Neurol Med Chir (Tokyo). 1991 Dec;31(12):787-91. doi: 10.2176/nmc.31.787.
The authors describe an unusual case of pulmonary small cell carcinoma with numerous calcified metastatic nodules of the brain in a 62-year-old female. Computed tomographic scanning and magnetic resonance imaging demonstrated these lesions with ring enhancement. Autopsy revealed about 30 calcified metastatic nodules in the brain, but no calcification in the pulmonary lesion. Histological examination of the brain lesions disclosed necrosis and calcification in the center and small cell carcinoma cells in the periphery.