Sanders Robert D, Maze Mervyn
Department of Anaesthetics, Intensive Care and Pain Medicine, Imperial College, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK.
Curr Opin Investig Drugs. 2007 Jan;8(1):25-33.
Alpha2-Adrenoceptor agonists have an immensely diverse utility in peri-operative and critical care medicine. In particular, their application as premedicants, analgesics and hypnotics/sedatives is becoming increasingly popular with delivery to a wide spectrum of patients. The ability of these agents to provide renal, cardiac and neurocognitive protection is only just being realized and requires further study.
α2肾上腺素能受体激动剂在围手术期和重症监护医学中有着极为广泛的用途。特别是,它们作为术前用药、镇痛药和催眠药/镇静药的应用在各类患者中的使用越来越普遍。这些药物提供肾脏、心脏和神经认知保护的能力才刚刚被认识到,还需要进一步研究。