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[正常受试者等时线图上的心脏激活过程]

[Heart activation course on isochrone maps in normal subjects].

作者信息

Laszki-Szczqchor Krystyna, Jagielski Józef, Sobieszczańska Małgorzata, Rusiecki Lesław

机构信息

Katedra i Zakład Patofizjologii Akademii Medycznej im. Piastów Slaskich, Wrocławiu.

出版信息

Pol Arch Med Wewn. 2006 Jun;115(6):512-9.

PMID:17263222
Abstract

Body surface potential mapping (BSPM) is a method providing a noninvasive assessment of the changes ongoing in the electric field of the heart. In the present study, the weakly recognized kind of the surface maps--isochrone maps that reflect in the best manner a pathway of the depolarization front propagation within the heart conduction system. BSPM was obtained using a HPM-7100 Fukuda Denshi system, which enables collecting a synchronic electrocardiographic recordings from 87 electrodes in the cylindrical system. The study population constituted 30 healthy subjects (15 females and 15 males) with the mean age of 23.9 +/- 4.56 years. The considered electrocardiogram from the all subjects appeared to be within the normative range. In order to obtain a pattern reflecting a depolarization trajectory in the human heart, the ventricular activation time maps (VAT), on the plane and superficial, were constructed with the own software. On the basis of the VAT maps obtained from the examined group, the group-mean VAT map for the normal subjects was created. Isochrone maps render much more information about heart activation spread than the standard 12-leads electrocardiography system. Using isochrone maps, one can monitor precisely a depolarization trajectory in the individual heart portions. The values and distribution of isochrones determine a velocity of activation propagation within the heart conduction system. Analysis of the isochrone maps collected in the normal subjects confirmed the activation pathway of the ventricles, starting from atrioventricular junction, via His bundle and its branches and finally to the myocardium through Purkinje fibres. In the examined group, no significant differences in relation to the isochrones distribution were found, therefore the group-mean VAT map was assumed as a reference pattern. The pattern of distribution and values of VAT map established for the normal subjects can be used in the further investigations concerning a diagnosis of the heart conduction system disturbances.

摘要

体表电位标测(BSPM)是一种对心脏电场中正在发生的变化进行无创评估的方法。在本研究中,一种较少被认识的体表图类型——等时线图,它能以最佳方式反映心脏传导系统内去极化波前传播的路径。使用福田电子株式会社的HPM - 7100系统获得BSPM,该系统能够在圆柱形系统中从87个电极同步采集心电图记录。研究对象为30名健康受试者(15名女性和15名男性),平均年龄为23.9±4.56岁。所有受试者的心电图均在正常范围内。为了获得反映人类心脏去极化轨迹的模式,利用自主软件构建了平面和表面的心室激活时间图(VAT)。基于从受检组获得的VAT图,创建了正常受试者的组平均VAT图。与标准的12导联心电图系统相比,等时线图能提供更多关于心脏激活传播的信息。使用等时线图,可以精确监测各个心脏部位的去极化轨迹。等时线的值和分布决定了心脏传导系统内激活传播的速度。对正常受试者采集的等时线图的分析证实了心室的激活途径,即从房室结开始,经希氏束及其分支,最后通过浦肯野纤维到达心肌。在受检组中,未发现与等时线分布相关的显著差异,因此将组平均VAT图作为参考模式。为正常受试者建立的VAT图的分布模式和值可用于进一步研究心脏传导系统紊乱的诊断。

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