卡氏肺孢子虫主要表面糖蛋白的表位研究及cDNA筛选
Epitope study and cDNA screening of major surface glycoprotein of Pneumocystis carinii.
作者信息
Nakamura Y, Kitada K, Wada M, Saito M
机构信息
Institute of Medical Science, University of Tokyo, Japan.
出版信息
J Protozool. 1991 Nov-Dec;38(6):3S-4S.
PMID:1726327
Abstract
Use of monoclonal antibodies against the major glycoprotein of Pneumocystis carinii (P115) implicated the sugar moiety as being strongly antigenic. Furthermore, monoclonal antibodies directed against the peptide portion of P115 were generated by using synthetic oligopeptides after amino acid sequencing was done on P115 proteolytic fragments.
摘要
使用针对卡氏肺孢子虫主要糖蛋白（P115）的单克隆抗体表明糖部分具有强抗原性。此外，在对P115蛋白水解片段进行氨基酸测序后，通过使用合成寡肽产生了针对P115肽部分的单克隆抗体。
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