通过多维筛选发现化学反应。
Discovery of chemical reactions through multidimensional screening.
作者信息
Beeler Aaron B, Su Shun, Singleton Chris A, Porco John A
机构信息
Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
出版信息
J Am Chem Soc. 2007 Feb 7;129(5):1413-9. doi: 10.1021/ja0674744.
PMID:17263426
Abstract
Multidimensional reaction screening of ortho-alkynyl benzaldehydes with a variety of catalysts and reaction partners was conducted in an effort to identify new chemical reactions. Reactions affording unique products were selected for investigation of preliminary scope and limitations.
摘要
为了确定新的化学反应，对邻炔基苯甲醛与多种催化剂和反应伙伴进行了多维反应筛选。选择了能产生独特产物的反应来研究其初步的适用范围和局限性。
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