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晚期胃癌患者出现类似急性皮炎的皮肤转移。

Cutaneous metastasis resembling acute dermatitis in patient with advanced gastric cancer.

作者信息

Koo D H, Chang H M, Jung J Y, Song J H, Lee J L, Ryu M H, Kim T W, Yook J H, Song J S, Lee J S, Kang Y K

机构信息

Department of Internal Medicine (Division of Oncology), Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Clin Exp Dermatol. 2007 May;32(3):284-6. doi: 10.1111/j.1365-2230.2007.02361.x. Epub 2007 Jan 30.

Abstract

The most common metastatic sites from gastric cancer are the liver, intra-abdominal lymph nodes, ovary and peritoneal cavity. Cutaneous metastasis of gastric cancer is rare, and most cutaneous metastases are typically solitary, nodular, have a firm consistency, and are red or hyperpigmented. Thus, cutaneous metastasis is easily distinguished from other skin disease. We report a case of a 60-year-old woman with cutaneous metastasis of gastric cancer, whose facial skin showed painless pruritic eczema, resembling acute dermatitis. She had earlier undergone a total gastrectomy for advanced gastric cancer in our hospital. After 14 months, she developed eczematous facial lesions; the presumptive diagnosis was acute dermatitis. However, skin biopsy unexpectedly revealed cutaneous metastasis of gastric cancer. After 6 months of systemic chemotherapy with capecitabine and cisplatin, the cutaneous metastasis was markedly improved and a clinically complete remission was accomplished.

摘要

胃癌最常见的转移部位是肝脏、腹腔淋巴结、卵巢和腹膜腔。胃癌皮肤转移罕见,大多数皮肤转移瘤通常为单发、结节状,质地硬,呈红色或色素沉着。因此,皮肤转移瘤很容易与其他皮肤病相鉴别。我们报告一例60岁女性胃癌皮肤转移患者,其面部皮肤出现无痛性瘙痒性湿疹,类似急性皮炎。她此前在我院因进展期胃癌接受了全胃切除术。14个月后,她面部出现湿疹样皮损;初步诊断为急性皮炎。然而,皮肤活检意外发现为胃癌皮肤转移。接受卡培他滨和顺铂全身化疗6个月后,皮肤转移明显改善,实现了临床完全缓解。

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