Salabé G B
Istituto di Medicina Sperimentale del CNR, Roma, Italy.
Thyroidology. 1990 Dec;2(3):125-8.
Following the introduction of echography it has became evident that a large proportion of nodules (15-37%) in euthyroid nodular goiter is entirely or partially cystic (20% in the A. experience). It is thought that cystic areas are subsequent to hemorrhagic necrosis occurring during goitrogenesis and therefore the term "pseudocysts" seems to be preferred. The article summarizes some hypothetical mechanisms of pseudocyst formation. In pseudocysts of recent onset a direct or indirect viral or bacterial etiology is suggested; in longstanding pseudocysts a deficient angiogenesis or immunotoxic mechanisms are proposed.
随着超声检查的引入，很明显，在甲状腺功能正常的结节性甲状腺肿中，很大一部分结节（15%-37%）完全或部分为囊性（根据A.的经验为20%）。据认为，囊性区域是甲状腺肿形成过程中发生的出血性坏死的结果，因此“假性囊肿”这一术语似乎更受青睐。本文总结了假性囊肿形成的一些假说机制。对于新近发生的假性囊肿，提示有直接或间接的病毒或细菌病因；对于长期存在的假性囊肿，则提出存在血管生成不足或免疫毒性机制。
