Yane Takehisa, Shinmori Hideyuki, Takeuchi Toshifumi
Graduate School of Science and Technology, Kobe University, Kobe 657-8501, Japan.
Org Biomol Chem. 2006 Dec 21;4(24):4469-73. doi: 10.1039/b612407k. Epub 2006 Nov 8.
Molecularly imprinted polymers bearing atrazine transforming activity were prepared by using newly designed templates that are atrazine analogues attached with an allyl or a styryl group via a disulfide bond at the 6-position, methacrylic acid as a functional monomer and styrene/divinylbenzene as crosslinkers. After polymerization, the disulfide bond was reduced to remove the atrazine moiety from the polymer matrix, followed by oxidation of the remaining thiol group to generate sulfonic acid (post-imprinting treatment), so that both a methacrylic acid residue and a sulfonic acid residue existed in an atrazine-imprinted cavity. The polymers indicated the selective binding of triazine herbicides and catalytic activity for methanolysis at the 6-position of atrazine, yielding a low toxic atraton.
通过使用新设计的模板制备具有阿特拉津转化活性的分子印迹聚合物，这些模板是在6位通过二硫键连接有烯丙基或苯乙烯基的阿特拉津类似物，以甲基丙烯酸作为功能单体，苯乙烯/二乙烯基苯作为交联剂。聚合后，二硫键被还原以从聚合物基质中去除阿特拉津部分，随后剩余的硫醇基团被氧化以生成磺酸（印迹后处理），从而使甲基丙烯酸残基和磺酸残基都存在于阿特拉津印迹腔中。这些聚合物表现出对三嗪类除草剂的选择性结合以及对阿特拉津6位甲醇解的催化活性，生成低毒的莠去通。
