Reyes-Mugica M, Chou P, Gonzalez-Crussi F, Tomita T
Department of Pathology, Children's Memorial Hospital, Northwestern University, Chicago, Illinois.
J Neurosurg. 1992 Jan;76(1):143-7. doi: 10.3171/jns.1992.76.1.0143.
A case of meningeal fibroma in a 5-year-old girl is described. The lesion presented as a benign intracranial tumor, eroding the frontal bone and protruding under the skin. It was composed of fibroblasts and collagen, embedded in a loose background with focal myxoid changes. The authors describe the patient's clinical presentation and the tumor's histological, immunohistochemical, and ultrastructural features, and discuss its differential diagnosis. It is concluded that fibromas of the meninges should be distinguished from fibroblastic meningiomas.
本文描述了一名5岁女孩的脑膜纤维瘤病例。该病变表现为良性颅内肿瘤,侵蚀额骨并突出于皮下。它由成纤维细胞和胶原蛋白组成,包埋于伴有局灶性黏液样变的疏松背景中。作者描述了患者的临床表现以及肿瘤的组织学、免疫组化和超微结构特征,并讨论了其鉴别诊断。结论是脑膜纤维瘤应与纤维母细胞型脑膜瘤相鉴别。