Duarte Andrezza Araújo de Oliveira, Nakatani Jorge, Rigueiro Moacyr Pezati, Saad Tânia
Hospital Santa Marcelina, São Paulo, SP, Brasil.
J Bras Pneumol. 2006 May-Jun;32(3):270-3.
Diffuse pulmonary ossification is a rare condition of unknown pathogenesis in which mature bone is found in the pulmonary parenchyma. It is almost invariably discovered as an incidental finding at autopsy. Most commonly, it affects middle-aged men and is asymptomatic. We present the case of a 75-year-old man in which the chest X-ray showed diffuse interstitial infiltrate. Diagnosis was based on histopathological examination by open-lung biopsy, which revealed interstitial fibrosis with pulmonary ossification.
弥漫性肺骨化是一种发病机制不明的罕见病症，在肺实质中可发现成熟骨组织。它几乎总是在尸检时偶然被发现。最常见的是，它影响中年男性且无症状。我们报告一例75岁男性病例，其胸部X线显示弥漫性间质浸润。诊断基于开胸肺活检的组织病理学检查，结果显示间质纤维化伴肺骨化。
