Chow James C L
Department of Radiation Oncology, University of Toronto and Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada.
Med Phys. 2007 Jan;34(1):175-82. doi: 10.1118/1.2403968.
Monte Carlo simulation was used to calculate the lateral buildup ratio (LBR) used in estimating the percentage depth dose (PDD) and dose per monitor unit for an irregular shaped cutout field in electron radiotherapy. Monte Carlo code BEAMnrc/EGSnrc was used to build a simulation model for a Varian 21 EX linear accelerator producing clinical electron beams with energies of 4, 6, 9, 12, and 16 MeV. The model is optimized by adjusting the incident electron energy within the Monte Carlo simulation so that the calculated PDD curves agree with the measurement within +/-2%. The LBR is calculated from the PDD curves for different diameters of circular cutouts. Although Monte Carlo simulation requires a longer time to create a LBR database compared to measurement using scanning water tank and dosimeter, the simulation models for different electron energies, applicators, and cutouts are very similar. As the calculations can be carried out in a batch mode automatically run by a computer, human efforts in carrying out measurements in the treatment room and fabricating the circular cutouts in the mold room are greatly saved. Moreover, the simulation avoids human error in the experimental setup and can better handle the electron scattering affecting accuracy in the measurement. Using Monte Carlo simulation to calculate the LBR is proved to be useful in the commissioning of the electron beams for electron radiotherapy.
蒙特卡罗模拟用于计算侧向积累因子(LBR),该因子用于估算电子放射治疗中不规则形状射野的百分深度剂量(PDD)和每监测单位剂量。使用蒙特卡罗代码BEAMnrc/EGSnrc为瓦里安21EX直线加速器构建模拟模型,该加速器能产生能量为4、6、9、12和16 MeV的临床电子束。通过在蒙特卡罗模拟中调整入射电子能量对模型进行优化,以使计算得到的PDD曲线与测量值在±2%范围内相符。根据不同直径圆形射野的PDD曲线计算LBR。尽管与使用扫描水箱和剂量仪进行测量相比,蒙特卡罗模拟创建LBR数据库需要更长时间,但不同电子能量、限光筒和射野的模拟模型非常相似。由于计算可以通过计算机自动以批处理模式进行,大大节省了在治疗室进行测量以及在模具室制作圆形射野的人力。此外,模拟避免了实验设置中的人为误差,并且能够更好地处理影响测量精度的电子散射。事实证明,使用蒙特卡罗模拟计算LBR对电子放射治疗的电子束调试很有用。