Guo Zhimou, Lei Aiwen, Liang Xinmiao, Xu Qing
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P. R. China.
Chem Commun (Camb). 2006 Nov 21(43):4512-4. doi: 10.1039/b610733h.
Click chemistry has been successfully extended into the field of preparation of functionalized HPLC packings, proving a novel facile and efficient strategy for covalently bonding stationary phases onto HPLC grade silica beads; the potential has been demonstrated by the preparation of "Click I-IV" columns and preliminary results in the separation of sugars.
点击化学已成功扩展到功能化高效液相色谱填料的制备领域,为将固定相共价键合到高效液相色谱级硅胶珠上提供了一种新颖、简便且高效的策略;“Click I-IV”柱的制备以及糖分离的初步结果已证明了这一潜力。