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点击化学:一种制备功能化高效液相色谱填料的简便有效新策略。

Click chemistry: a new facile and efficient strategy for preparation of functionalized HPLC packings.

作者信息

Guo Zhimou, Lei Aiwen, Liang Xinmiao, Xu Qing

机构信息

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P. R. China.

出版信息

Chem Commun (Camb). 2006 Nov 21(43):4512-4. doi: 10.1039/b610733h.

Abstract

Click chemistry has been successfully extended into the field of preparation of functionalized HPLC packings, proving a novel facile and efficient strategy for covalently bonding stationary phases onto HPLC grade silica beads; the potential has been demonstrated by the preparation of "Click I-IV" columns and preliminary results in the separation of sugars.

摘要

点击化学已成功扩展到功能化高效液相色谱填料的制备领域,为将固定相共价键合到高效液相色谱级硅胶珠上提供了一种新颖、简便且高效的策略;“Click I-IV”柱的制备以及糖分离的初步结果已证明了这一潜力。

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