Málly Judit, Stone Trevor W
Department of Neurorehabilitation, Institute of Neurorehabilitation, Sopron, Hungary.
Expert Rev Neurother. 2007 Feb;7(2):165-77. doi: 10.1586/14737175.7.2.165.
Transcranial magnetic stimulation (TMS) can directly stimulate the CNS, modifying the brain's plasticity to enhance the behavior of the paretic extremities. Studies with low-frequency repetitive TMS (rTMS) on the intact hemisphere and those with high frequencies on the affected hemisphere could increase the speed of movement in the hand affected by CNS injury. Stimulation of the motor pathway may contribute to faster improvement in patients with spinal cord injury. Symptoms of Parkinson's disease (such as cognition and working memory, neglect syndrome and global aphasia) can be influenced by rTMS. However, the site of stimulation and the parameters of rTMS are different. Processes that contribute to the behavior of rTMS include the modification of brain plasticity, induction of neurogenesis, growth of new fibers in the spinal cord or all of these together. According to previous research, rTMS may be suitable as an add-on therapy to rehabilitation in CNS diseases.
经颅磁刺激（TMS）可直接刺激中枢神经系统（CNS），改变大脑可塑性，以改善瘫痪肢体的行为。对完整半球进行低频重复经颅磁刺激（rTMS）以及对患侧半球进行高频刺激的研究，可提高受中枢神经系统损伤影响的手部运动速度。刺激运动通路可能有助于脊髓损伤患者更快恢复。帕金森病的症状（如认知和工作记忆、忽视综合征和完全性失语）可受rTMS影响。然而，刺激部位和rTMS参数有所不同。促成rTMS行为的过程包括大脑可塑性的改变、神经发生的诱导、脊髓中新纤维的生长或所有这些因素共同作用。根据先前的研究，rTMS可能适合作为中枢神经系统疾病康复的辅助治疗方法。
