Rhew Isaac, Yasui Yutaka, Sorensen Bess, Ulrich Cornelia M, Neuhouser Marian L, Tworoger Shelley S, Chubak Jessica, Bowen Deborah J, McTiernan Anne
Fred Hutchinson Cancer Research Center, Cancer Prevention Program, University of Washington, School of Public Health and Community Medicine, Department of Epidemiology, Seattle, WA, 98109-1024, United States.
Contemp Clin Trials. 2007 Jul;28(4):472-81. doi: 10.1016/j.cct.2007.01.002. Epub 2007 Jan 12.
Little is known about whether initiating physical activity induces change in other health-related behaviors. If other behaviors do change with increasing physical activity, this would complicate interpretation of differences in study outcomes in exercise intervention trials.
Randomized controlled trial.
SETTING/PARTICIPANTS: 173 sedentary, overweight (body mass index between 24.0 and 25.0 kg/m2 with body fat>33% or BMI>or=25.0 kg/m2), postmenopausal women, ages 50 to 75 years, not using hormone therapy, and living in the Seattle, WA area.
Participants were randomly assigned to an exercise intervention (n=87) or a stretching-control group (n=86). The exercise intervention included facility and home-based moderate-intensity exercise.
Changes in dietary intake, alcohol consumption, and medication and supplement use were compared from baseline to 3- and 12-month follow-up between exercise and control groups, and by tertiles of exercise adherence. Data were collected between January 1998 and July 2001.
In general, changes in dietary intake between the exercise and control group were not statistically different. The exercise group had a greater increase in the proportion of participants who used multivitamins (+5%) compared to the control group (-10%) at 3 months (p-interaction=0.04), but not at 12 months (p-interaction=0.58). Furthermore, there were few differences when comparing changes in health behaviors across exercise adherence tertiles.
Our results suggest that participation in a year-long exercise intervention trial among post-menopausal women has little effect on other health behaviors. These findings suggest that additional behavior changes in exercise trials are minimal and unlikely to bias primary study results.
关于开始体育活动是否会引发其他与健康相关行为的改变,目前所知甚少。如果其他行为确实会随着体育活动的增加而改变,这将使运动干预试验中研究结果差异的解读变得复杂。
随机对照试验。
设置/参与者:173名久坐不动、超重(体重指数在24.0至25.0kg/m²之间且体脂>33%或体重指数≥25.0kg/m²)、绝经后、年龄在50至75岁之间、未使用激素疗法且居住在华盛顿州西雅图地区的女性。
参与者被随机分配到运动干预组(n = 87)或伸展对照组(n = 86)。运动干预包括在健身设施和家中进行的中等强度运动。
比较运动组和对照组从基线到3个月及12个月随访期间饮食摄入量、酒精消费量、药物和补充剂使用情况的变化,并按运动依从性三分位数进行比较。数据收集时间为1998年1月至2001年7月。
总体而言,运动组和对照组之间饮食摄入量的变化无统计学差异。在3个月时,运动组使用多种维生素的参与者比例增加幅度更大(+5%),而对照组则下降(-10%)(交互作用p = 0.04),但在12个月时无此差异(交互作用p = 0.58)。此外,比较不同运动依从性三分位数的健康行为变化时,差异很少。
我们的数据表明,绝经后女性参与为期一年的运动干预试验对其他健康行为影响很小。这些发现表明,运动试验中额外的行为变化很小,不太可能使主要研究结果产生偏差。