外耳道激光针刺激对人脑干及极早期听觉诱发电位的影响。
Effects of laserneedle stimulation in the external auditory meatus on brainstem and very early auditory evoked potentials in humans.
作者信息
Litscher G
机构信息
Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, Medical University Graz, Austria.
出版信息
Neurol Res. 2006 Dec;28(8):837-40. doi: 10.1179/016164106X110373.
OBJECTIVES
For the first time, brainstem auditory evoked potentials (BAEP) and very early auditory evoked potentials (EAEP) were investigated in 23 volunteers (mean age: 26.5 +/- 3.6 years) under resting conditions and during continuous and frequency modulated (2 Hz) laser stimulation in the external auditory meatus.
METHODS
Using a new ear adapter, the outer region of the auditory canal was stimulated with laser light (685 nm, 4 x 30-40 mW, duration: 10 minutes).
RESULTS
The EAEPs were significantly changed during continuous (p=0.019), as well as frequency modulated (p=0.014) laser stimulation compared with control measurements.
DISCUSSION
Physiologic alterations of inner ear mechanism such as extra-cerebral changes in conductance or stimulation-dependent depolarization processes in extra-cerebral regions of the auditory system could be possible explanations for the significant difference in measurement parameters.
目的
首次在23名志愿者（平均年龄：26.5±3.6岁）处于静息状态以及在外耳道进行连续和频率调制（2赫兹）激光刺激期间，对脑干听觉诱发电位（BAEP）和极早期听觉诱发电位（EAEP）进行了研究。
方法
使用一种新型耳适配器，用激光（685纳米，4×30 - 40毫瓦，持续时间：10分钟）刺激外耳道外部区域。
结果
与对照测量相比，在连续（p = 0.019）以及频率调制（p = 0.014）激光刺激期间，极早期听觉诱发电位发生了显著变化。
讨论
内耳机制的生理改变，如听觉系统脑外区域电导的脑外变化或刺激依赖性去极化过程，可能是测量参数存在显著差异的原因。
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