[爱泼斯坦-巴尔病毒感染血清学特征的年龄分布：诊断实验室结果综述]
[Age distribution of serological profiles of Epstein-Barr virus infection: review of results from a diagnostic laboratory].
作者信息
Pariente Macarena, Bartolomé Joaquín, Lorente Santiago, Crespo María Dolores
机构信息
Laboratorio de Microbiología, Complejo Hospitalario Universitario de Albacete, España.
出版信息
Enferm Infecc Microbiol Clin. 2007 Feb;25(2):108-10. doi: 10.1157/13098571.
INTRODUCTION
The objective of this study was to examine the distribution of serological profiles of Epstein-Barr virus (EBV) infection according to age.
METHODS
We retrospectively review EBV specific antibody determinations performed at our hospital between 2003 and 2004.
RESULTS
The distribution of acute EBV infection by age showed a bimodal pattern, with peaks at the age of 2-4 years and 14-18 years. Among the 21-30 year-old age group, there was a higher percentage of seronegative men than women. Seroprevalence in patients aged 31 years or more was 99%.
CONCLUSIONS
Most primary EBV infections occur in early childhood or adolescence. The increase in seroprevalence takes place at an earlier age in females than in males. EBV seroprevalence in adult patients is very high.
引言
本研究的目的是根据年龄检查爱泼斯坦-巴尔病毒（EBV）感染的血清学特征分布情况。
方法
我们回顾性分析了2003年至2004年在我院进行的EBV特异性抗体检测。
结果
急性EBV感染的年龄分布呈双峰模式，在2至4岁和14至18岁出现峰值。在21至30岁年龄组中，血清阴性男性的比例高于女性。31岁及以上患者的血清阳性率为99%。
结论
大多数原发性EBV感染发生在幼儿期或青春期。女性血清阳性率的上升比男性早。成年患者的EBV血清阳性率非常高。
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