Campos Vicente, Adrio Belén, Estévez Francisco, Mosquera Víctor X, Pérez Javier, Cuenca José J, Herrera José M, Valle José V, Portela Francisco, Rodríguez Fernando, Juffé Alberto
Servicio de Cirugía Cardiaca, Hospital Universitario Juan Canalejo, A Coruña, Spain.
Rev Esp Cardiol. 2007 Jan;60(1):45-50.
The Cryolife O'Brien xenograft is a stentless bioprosthesis constructed from noncoronary leaflets from three porcine aortic valves. The aim of this study was to investigate short-term results after aortic valve replacement with this composite xenograft.
Since October 1993, Cryolife O'Brien bioprostheses have been implanted in 210 patients. The patients' mean age was 70.9 (7.5) years (range 23-83 years). The indication was aortic stenosis in 132 cases, aortic insufficiency in 25 cases, and both lesions in 53 cases. Valve function was studied by echocardiography preoperatively, at discharge, and 6 and 12 months postoperatively.
The 30-day mortality rate was 5.2% (11/210). Over time, the mean gradients decreased and the effective area index increased. In addition, the left ventricular mass index, wall thickness, and septum thickness also decreased shortly after surgery.
Use of the Cryolife O'Brien stentless bioprosthesis demonstrated satisfactory results at 1-year follow-up. Additional follow-up is required to assess the performance of this bioprosthesis over the long term.
Cryolife奥布赖恩异种移植物是一种无支架生物假体，由三个猪主动脉瓣的非冠状动脉瓣叶构建而成。本研究的目的是调查使用这种复合异种移植物进行主动脉瓣置换术后的短期结果。
自1993年10月以来，Cryolife奥布赖恩生物假体已植入210例患者体内。患者的平均年龄为70.9（7.5）岁（范围23 - 83岁）。适应症为单纯主动脉瓣狭窄132例，单纯主动脉瓣关闭不全25例，两者并存53例。术前、出院时以及术后6个月和12个月通过超声心动图研究瓣膜功能。
30天死亡率为5.2%（11/210）。随着时间推移，平均压力阶差降低，有效面积指数增加。此外，术后不久左心室质量指数、室壁厚度和室间隔厚度也降低。
在1年随访中，使用Cryolife奥布赖恩无支架生物假体显示出令人满意的结果。需要进一步随访以评估这种生物假体的长期性能。
