Toda Masahiro, Den Rei, Nagasawa Shingo, Kitamura Kazuyuki, Morimoto Kanehisa
Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Japan.
Arch Environ Occup Health. 2005 Sep-Oct;60(5):266-9. doi: 10.3200/AEOH.60.5.266-269.
The authors evaluated individuals' lifestyles and investigated the relationship between lifestyle scores and the incidence of salivary stress markers cortisol and chromogranin A (CgA). Saliva samples from 173 healthy male workers were tested by enzyme-linked immunosorbent assay for salivary cortisol and CgA levels. Questionnaires concerning lifestyle were administered: respondents aged 20-39 years who had good scores for comprehensive lifestyle showed significantly lower levels of cortisol than did respondents with moderate or poor comprehensive lifestyle scores. Respondents aged 40-59 who scored better for general lifestyle than they did during the previous year showed significantly lower levels of CgA than did respondents reporting no improvement. These findings suggest that levels of salivary cortisol may be affected by current circumstances and that levels of CgA may be affected by changes in comprehensive lifestyle.
作者评估了个体的生活方式，并研究了生活方式得分与唾液应激标志物皮质醇和嗜铬粒蛋白A（CgA）发病率之间的关系。通过酶联免疫吸附测定法对173名健康男性工人的唾液样本进行检测，以测定唾液皮质醇和CgA水平。发放了有关生活方式的问卷：20至39岁的受访者中，综合生活方式得分高的人唾液皮质醇水平明显低于综合生活方式得分中等或较差的受访者。40至59岁的受访者中，总体生活方式得分比上一年有所提高的人唾液CgA水平明显低于那些表示没有改善的受访者。这些发现表明，唾液皮质醇水平可能受当前环境影响，而CgA水平可能受综合生活方式变化的影响。
