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童年逆境、近期生活事件与晚年抑郁症

Childhood adversity, recent life events and depression in late life.

作者信息

Comijs Hannie C, Beekman Aartjan T F, Smit Filip, Bremmer Marijke, van Tilburg Theo, Deeg Dorly J H

机构信息

Department of Psychiatry, EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

J Affect Disord. 2007 Nov;103(1-3):243-6. doi: 10.1016/j.jad.2007.01.012. Epub 2007 Feb 8.

Abstract

BACKGROUND

The study investigates whether persons who have experienced childhood adversity are more likely to develop depressive symptoms when faced with recent events.

METHOD

Data were used from a population-based sample, aged 55 to 85 years (n=1887), which were not depressed at baseline. Childhood adversities and recent stressful life events were retrospectively assessed. Depressive symptoms were measured with the CES-D.

RESULTS

14.4% of our sample experienced adverse events during childhood (<18 yrs) and 35.4% experienced recent events. Associations of depressive symptoms were found with both, childhood adversity (OR 1.80, 95% CI 1.21-2.69) and recent life events (OR 1.42, 95% CI 1.01-2.00). The effect of recent events on depressive symptoms was not modified by childhood adversity.

LIMITATIONS

Underreporting may be present due to unwillingness to report embarrassing events or to disclose painful memories.

CONCLUSIONS

No evidence was found for the assumption that older persons were more vulnerable for depression in reaction to recent life events when they were exposed to childhood adversity.

摘要

背景

本研究调查了经历过童年逆境的人在面对近期事件时是否更有可能出现抑郁症状。

方法

使用了来自一个基于人群的样本的数据,样本年龄在55至85岁之间(n = 1887),基线时无抑郁症状。对童年逆境和近期压力性生活事件进行了回顾性评估。使用流调中心用抑郁量表(CES-D)测量抑郁症状。

结果

我们样本中的14.4%在童年时期(<18岁)经历过不良事件,35.4%经历过近期事件。发现抑郁症状与童年逆境(比值比1.80,95%置信区间1.21 - 2.69)和近期生活事件(比值比1.42,95%置信区间1.01 - 2.00)均有关联。近期事件对抑郁症状的影响未因童年逆境而改变。

局限性

由于不愿报告尴尬事件或披露痛苦记忆,可能存在报告不足的情况。

结论

没有证据支持这样的假设,即老年人在童年时期经历过逆境,在面对近期生活事件时更容易因反应而患上抑郁症。

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