McPhee James T, Asham Emad H, Rohrer Michael J, Singh Michael J, Wong Geoffrey, Vorhies Robert W, Nelson Peter R, Cutler Bruce S
Division of Vascular Surgery, University of Massachusetts Medical Center, Worcester, Massachusetts 01655, USA.
J Surg Res. 2007 Apr;138(2):181-8. doi: 10.1016/j.jss.2006.09.039. Epub 2007 Feb 9.
Several publications document the technical feasibility of stent graft repair of aortic transection. We report our mid-term results of endovascular repair of thoracic aortic transections using covered stent grafts and compare this to a cohort undergoing open repair during the same time period to demonstrate the shift in practice pattern at our institution.
A retrospective review of patients who sustained blunt thoracic transection was undertaken. Medical records were examined to identify the clinical outcome of the procedure, and follow-up CT scans were reviewed to document adequate treatment of the transection. Outcome measures include procedure-related mortality, neurological morbidity, and successful immediate and mid-term coverage of the thoracic false aneurysm and absence of graft migration or endoleak.
From July, 2000 to October, 2004, 27 patients were identified with descending thoracic aortic transection at our level I trauma center. Fourteen patients were managed nonoperatively, five patients underwent thoracotomy and direct aortic repair, and eight patients underwent endoluminal stent graft repair. Of the endovascular group (n=8), repairs were performed with stacked AneuRx aortic cuffs (Medtronic, Inc., Minneapolis, MN) (n = 6), a Gore thoracic aortic stent graft (Thoracic EXCLUDER; W.L. Gore, Flagstaff, AZ) (n=1), or a Medtronic Talent thoracic endograft (Medtronic, Inc.) (n=1). Access for stent graft deployment was the common femoral artery (n=2), iliac artery (n=4), or distal abdominal aorta (n=2). Completion arch aortography and postoperative CT scanning confirmed successful management of the aortic transection in each patient. There were no procedure-related deaths, paraplegia, or stroke. Postoperative complications included a brachial artery thrombosis in one patient as well as an external iliac artery dissection and acute renal failure in a second patient for a complication rate of 37.5%. Two patients died as a result of their injuries unrelated to the stent graft repair. Mean follow-up of 16.6 mo has shown no evidence of endoleak or stent graft migration. Of the open repair group (n=5), one patient died in the operating room during attempted aortic repair, and one patient had a postoperative stroke.
Due to technical success and absence of delayed complications including endoleak and graft migration, stent graft repair of traumatic aortic transection has replaced open aortic repair as the primary treatment modality in the multiply injured trauma patient at our institution. The postoperative complication rate observed in this small series tempers the success to some degree, but the severity of the complications compares favorably with those observed in the open repair group.
多篇文献记载了主动脉横断覆膜支架修复术的技术可行性。我们报告了使用覆膜支架对胸主动脉横断进行血管腔内修复的中期结果,并将其与同期接受开放修复的一组患者进行比较,以展示我院治疗模式的转变。
对钝性胸主动脉横断患者进行回顾性研究。查阅病历以确定手术的临床结果,并复查随访CT扫描以记录横断的充分治疗情况。观察指标包括手术相关死亡率、神经功能障碍,以及胸段假性动脉瘤的即刻和中期成功覆盖情况,且无移植物移位或内漏。
2000年7月至2004年10月,我院一级创伤中心共确诊27例降主动脉横断患者。14例患者接受非手术治疗,5例患者接受开胸直接主动脉修复,8例患者接受血管腔内支架修复。血管腔内修复组(n = 8)中,6例使用堆叠式AneuRx主动脉套囊(美敦力公司,明尼阿波利斯,明尼苏达州)进行修复,1例使用戈尔胸主动脉覆膜支架(Thoracic EXCLUDER;W.L.戈尔公司,弗拉格斯塔夫,亚利桑那州),1例使用美敦力Talent胸段腔内移植物(美敦力公司)。支架置入的入路为股总动脉(n = 2)、髂动脉(n = 4)或腹主动脉远端(n = 2)。完成主动脉弓造影和术后CT扫描证实每位患者的主动脉横断均得到成功处理。无手术相关死亡、截瘫或卒中发生。术后并发症包括1例肱动脉血栓形成,以及第2例患者的髂外动脉夹层和急性肾衰竭,并发症发生率为37.5%。2例患者因与支架修复无关的损伤死亡。平均随访16.6个月,未发现内漏或支架移位迹象。开放修复组(n = 5)中,1例患者在主动脉修复尝试过程中死于手术室,1例患者术后发生卒中。
由于技术成功且无包括内漏和移植物移位在内的延迟并发症,创伤性主动脉横断的支架修复已取代开放主动脉修复,成为我院多发伤创伤患者的主要治疗方式。本小系列观察到的术后并发症发生率在一定程度上影响了成功率,但并发症的严重程度与开放修复组相比更有利。