Dom Geert, De Wilde Bieke, Hulstijn Wouter, Sabbe Bernard
Psychiatric Centre Brothers Alexians, 2530 Boechout, Belgium.
Compr Psychiatry. 2007 Mar-Apr;48(2):178-85. doi: 10.1016/j.comppsych.2006.08.004. Epub 2006 Dec 8.
Childhood traumatic experiences have been suggested to relate to early-onset alcoholism and to negatively influence the severity and course of alcohol use disorders. Early-onset alcoholic (n = 54) and late-onset alcoholic (n = 65) inpatients were compared as to the severity of their childhood traumatic experiences, prevalence of current and lifetime posttraumatic stress disorder (PTSD), and depressive symptoms. The early-onset alcoholic patients had a higher number and more severe childhood traumatic experiences compared with the late-onset alcoholic patients. More female than male alcohol-dependent patients had lifetime PTSD diagnosis. Finally, specifically within the female alcoholic patients the severity of early childhood experiences was positively associated with the severity of current substance use and related problems. Within early-onset alcoholic treatment-seeking populations, active screening for childhood traumatic experiences and current PTSD is advised in view of treatment planning.
童年创伤经历被认为与早发性酒精中毒有关,并对酒精使用障碍的严重程度和病程产生负面影响。对早发性酒精中毒(n = 54)和晚发性酒精中毒(n = 65)的住院患者进行了比较,比较内容包括他们童年创伤经历的严重程度、当前和终生创伤后应激障碍(PTSD)的患病率以及抑郁症状。与晚发性酒精中毒患者相比,早发性酒精中毒患者有更多且更严重的童年创伤经历。酒精依赖患者中,终生被诊断为PTSD的女性多于男性。最后,具体在女性酒精中毒患者中,童年早期经历的严重程度与当前物质使用及相关问题的严重程度呈正相关。鉴于治疗规划,建议在寻求早发性酒精中毒治疗的人群中积极筛查童年创伤经历和当前的PTSD。