Evren Cuneyt, Can Suat, Evren Bilge, Saatcioglu Omer, Cakmak Duran
Bakirkoy State Hospital for Psychiatric and Neurological Disorders, AMATEM (Alcohol and Drug Research, Treatment and Training Center), Istanbul, Turkey.
Psychiatry Clin Neurosci. 2006 Feb;60(1):77-84. doi: 10.1111/j.1440-1819.2006.01463.x.
The aim of the present study was to evaluate the prevalence of lifetime posttraumatic stress disorder (PTSD) in Turkish male alcohol-dependent inpatients, and to investigate the relationship of lifetime PTSD diagnosis with anxiety, depression, hopelessness, erectile dysfunction and psychosocial problems related with alcohol dependency. Eighty-two male inpatients who met DSM-IV criteria for alcohol dependence and 48 subjects without substance use disorder as a control group were included in the study. Subjects were applied the Hamilton Depression Rating Scale (HAM-D), the Hamilton Anxiety Rating Scale (HAM-A), the Michigan Alcoholism Screening Test (MAST), the Beck Hopelessness Scale (BHS) and the International Index of Erectile Function (IIEF). Rate of lifetime PTSD diagnosis was found to be 26.8% among alcohol-dependent inpatients. The mean age of patients with lifetime PTSD was lower than in patients without this diagnosis, while there were no significant differences between these two groups in terms of age of first alcohol use, lifetime major depression, current depression, presence and severity of erectile dysfunction. Mean scores of HAM-D, HAM-A, BHS and MAST in the group with lifetime PTSD were significantly higher than the group without this diagnosis. There was a positive relationship between lifetime PTSD diagnosis and depression, anxiety, hopelessness and severity of psychosocial problems related to alcohol dependency, while there was no relationship between lifetime PTSD comorbidity and erectile dysfunction in alcohol-dependent patients.
本研究的目的是评估土耳其男性酒精依赖住院患者中终生创伤后应激障碍(PTSD)的患病率,并调查终生PTSD诊断与焦虑、抑郁、绝望、勃起功能障碍以及与酒精依赖相关的心理社会问题之间的关系。该研究纳入了82名符合DSM-IV酒精依赖标准的男性住院患者和48名无物质使用障碍的受试者作为对照组。对受试者应用了汉密尔顿抑郁量表(HAM-D)、汉密尔顿焦虑量表(HAM-A)、密歇根酒精ism筛查测试(MAST)、贝克绝望量表(BHS)和国际勃起功能指数(IIEF)。在酒精依赖住院患者中,终生PTSD诊断率为26.8%。有终生PTSD的患者的平均年龄低于无此诊断的患者,而在首次饮酒年龄、终生重度抑郁、当前抑郁、勃起功能障碍的存在和严重程度方面,这两组之间没有显著差异。有终生PTSD的组中HAM-D、HAM-A、BHS和MAST的平均得分显著高于无此诊断的组。终生PTSD诊断与抑郁、焦虑、绝望以及与酒精依赖相关的心理社会问题的严重程度之间存在正相关,而在酒精依赖患者中,终生PTSD共病与勃起功能障碍之间没有关系。