Jerzmanowski Andrzej
Laboratory of Plant Molecular Biology, Warsaw University and Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Biochim Biophys Acta. 2007 May-Jun;1769(5-6):330-45. doi: 10.1016/j.bbaexp.2006.12.003. Epub 2007 Jan 8.
In yeast and mammals, ATP-dependent chromatin remodeling complexes belonging to the SWI/SNF family play critical roles in the regulation of transcription, cell proliferation, differentiation and development. Homologs of conserved subunits of SWI/SNF-type complexes, including several putative ATPases and other core subunits, have been identified in plants. Here I summarize recent insights in structural organization and functional diversification of putative plant SWI/SNF-type chromatin remodeling complexes and discuss in a broader evolutionary perspective the similarities and differences between plant and yeast/animal SWI/SNF remodeling. I also summarize the current view of localization in nucleosome and dynamic behaviour in chromatin of linker (H1) histones and discuss significance of recent findings indicating that in both plants and mammals histone H1 is involved in determining patterns of DNA methylation at selected loci.
在酵母和哺乳动物中，属于SWI/SNF家族的ATP依赖性染色质重塑复合物在转录调控、细胞增殖、分化和发育中发挥着关键作用。在植物中已鉴定出SWI/SNF型复合物保守亚基的同源物，包括几种假定的ATP酶和其他核心亚基。在此，我总结了关于假定的植物SWI/SNF型染色质重塑复合物的结构组织和功能多样化的最新见解，并从更广泛的进化角度讨论了植物与酵母/动物SWI/SNF重塑之间的异同。我还总结了目前关于连接组蛋白（H1）在核小体中的定位及其在染色质中的动态行为的观点，并讨论了最近研究结果的意义，这些结果表明在植物和哺乳动物中，组蛋白H1都参与确定选定基因座处的DNA甲基化模式。
